NLRP6 Rabbit monoclonal antibody

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SKU:: A28419
Zusätzliche Namen:: AVR|CLR11.4|NALP6|NAVR|NAVR/AVR|PAN3|PYPAF5
Anwendung:: ELISA, WB
Molekulargewicht:: 99 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P59044
Synonyme:: angiotensin II/vasopressin receptor;AVR;CLR11.4;NACHT, leucine rich repeat and PYD containing 6;NACHT, LRR and PYD domains-containing protein 6;NALP6;NAVR;NAVR/AVR;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN-containing APAF1-like protein 5
Weitere Details:: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.