Nephrin Rabbit monoclonal antibody

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SKU:: A28348
Zusätzliche Namen:: nephrin|NephrinB
Anwendung:: ELISA, WB, IHC-P, IF
Molekulargewicht:: 135-200 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: LGDSGLTDKGIQVSITTPGLDQAPEDTDQPLPTEQPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSEEDRIRNEYEESQWTGDRDTRSSTVSTAEVDPHYYSMRDFSPQLPPTLEEVSYRQAFTGIEDEDMAFPGHLYDEVERVYGPPGVWGPLYDEVQMDPYDLRWPEVKYEDPRGIYDQVAADMDAGEPGSLPFELRGHLV
Uniprot:: Q9QZS7
Synonyme:: CNF;ne;nephrin;nephrin 1;NephrinB;nephrosis 1 homolog, nephrin;nephrosis 1, congenital, Finnish type (nephrin);NPHN;NPHS1, nephrin;renal glomerulus-specific cell adhesion receptor;truncated NPHS1
Weitere Details:: Predicted to enable cell adhesion molecule binding activity; cytoskeletal protein binding activity; and protein domain specific binding activity. Involved in myoblast fusion; skeletal muscle tissue development; and slit diaphragm assembly. Acts upstream of or within several processes, including JNK cascade; cell adhesion; and positive regulation of actin filament polymerization. Located in cell projection; focal adhesion; and plasma membrane. Is active in cell periphery. Is expressed in central nervous system; metanephros; and skeletal muscle. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 1. Orthologous to human NPHS1 (NPHS1 adhesion molecule, nephrin).

Versandbedingungen:: Blue Ice