PE Rabbit anti-Human CD8 PolymAb[R]

Größe

Auf Anfrage

SKU:: A28209PM
Zusätzliche Namen:: CD8|CD8alpha|CD8B1|CD8beta.|IMD116|Leu2|Ly-3|LY3|LYT3|p32|P37
Anwendung:: Flow Cytometry
Molekulargewicht:: Refer to figures
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P01732, P10966
Synonyme:: CD8;CD8 antigen, alpha polypeptide (p32);CD8 antigen, beta polypeptide 1 (p37);CD8B1;Leu2;Leu2 T-lymphocyte antigen;LY3;LYT3;OKT8 T-cell antigen;p32;P37;T cell co-receptor;T lymphocyte surface glycoprotein beta chain;T-cell antigen Leu2;T-cell surface glycoprotein CD8 alpha chain;T-cell surface glycoprotein CD8 beta chain;T-lymphocyte differentiation antigen T8/Leu-2;T8 T-cell antigen
Weitere Details:: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.

Versandbedingungen:: Blue Ice