SERPINE1 Rabbit monoclonal antibody

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£169.00

SKU:: A27796
Zusätzliche Namen:: PAI|PAI-1|PAI1|PLANH1
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 48 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P05121
Synonyme:: endothelial plasminogen activator inhibitor;PAI;PAI-1;PAI1;PLANH1;plasminogen activator inhibitor 1;serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;serpin E1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Weitere Details:: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.