[KD Validated] Bcl-2 Rabbit PolymAb[R]

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SKU:: A27315PM
Zusätzliche Namen:: Bcl-2|PPP1R50
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 26 kDa
Spezies-Reaktivität:: Human, Rat
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Uniprot:: P10415, P49950
Synonyme:: apoptosis regulator Bcl-2;B cell lymphoma 2 associated oncogene;B-cell CLL/lymphoma 2;B-cell leukemia/lymphoma 2;Bcl-2;Bcl-2alpha;Bcl2-like protein;PPP1R50;protein phosphatase 1, regulatory subunit 50
Weitere Details:: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.