[KD Validated] ADAR1 Rabbit monoclonal antibody

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SKU:: A27294
Zusätzliche Namen:: ADAR1|AGS6|DRADA|DSH|DSRAD|G1P1|IFI-4|IFI4|K88DSRBP|P136
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 110kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPV
Uniprot:: P55265
Synonyme:: 136 kDa double-stranded RNA-binding protein;ADAR1;adenosine deaminase acting on RNA 1-A;AGS6;double-stranded RNA-specific adenosine deaminase;DRADA;DSH;DSRAD;dsRNA adenosine deaminase;dsRNA adeonosine deaminase;G1P1;IFI-4;IFI4;interferon-induced protein 4;interferon-inducible protein 4;K88DSRBP;P136
Weitere Details:: This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.