NeuN Mouse monoclonal antibody

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SKU:: A26951
Zusätzliche Namen:: FOX-3|FOX3|HRNBP3|NEUN
Anwendung:: ELISA, WB, IHC-P, IF
Molekulargewicht:: 46-55 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: A6NFN3
Synonyme:: fox-1 homolog C;FOX-3;FOX3;hexaribonucleotide binding protein 3;HRNBP3;NEUN;neuN antigen;neuronal nuclei antigen;RNA binding protein fox-1 homolog 3;RNA binding protein, fox-1 homolog 3
Weitere Details:: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.