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A25000

CaMKII Rabbit monoclonal antibody

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SKU:
A25000
Zusätzliche Namen:
CAMKA|CaMKII|CaMKIIalpha|CaMKIINalpha|MRD53|MRT63
Anwendung:
ELISA, WB
Molekulargewicht:
50 kDa/60 kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
GVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
Uniprot:
Q13554, Q13555, Q13557, Q9UQM7
Synonyme:
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha;calcium/calmodulin-dependent protein kinase (CaM kinase) II delta;calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma;calcium/calmodulin-dependent protein kinase II alpha-B subunit;calcium/calmodulin-dependent protein kinase type II alpha chain;calcium/calmodulin-dependent protein kinase type II delta chain;calcium/calmodulin-dependent protein kinase type II subunit alpha;calcium/calmodulin-dependent protein kinase type II subunit beta;calcium/calmodulin-dependent protein kinase type II subunit delta;calcium/calmodulin-dependent protein kinase type II subunit gamma;CaM kinase II alpha subunit;CaM kinase II beta subunit;CaM kinase II delta subunit;caM kinase II subunit alpha;CaM-kinase II alpha chain;CaM-kinase II beta chain;CaM-kinase II delta chain;CAM2;CAMK;CAMK-II;CaMK-II alpha subunit;CaMK-II delta subunit;caMK-II subunit alpha;caMK-II subunit beta;caMK-II subunit gamma;CAMK2;CAMKA;CAMKB;CAMKD;CAMKG;CaMKIIalpha;CaMKIIbeta;CaMKIINalpha;MRD53;MRD54;MRD59;MRT63;proline rich calmodulin-dependent protein kinase
Weitere Details:
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Versandbedingungen:
Blue Ice