[KD Validated] PSMA7 Rabbit monoclonal antibody

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SKU:: A24916
Zusätzliche Namen:: [KD Validated] PSMA7|C6|HEL-S-276|HSPC|RC6-1|XAPC7
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 28kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: SGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKKKQKKAS
Uniprot:: O14818
Synonyme:: C6;epididymis secretory protein Li 276;HEL-S-276;HSPC;proteasome (prosome, macropain) subunit, alpha type, 7;proteasome subunit alpha 4;proteasome subunit alpha 7;proteasome subunit alpha type-7;proteasome subunit RC6-1;proteasome subunit XAPC7;RC6-1;testicular tissue protein Li 151;XAPC7
Weitere Details:: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Versandbedingungen:: Blue Ice