A24848
CCL5 Rabbit polyclonal antibody
Größe
£152.00
- SKU:
- A24848
- Zusätzliche Namen:
- C-C motif chemokine 5
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 13kDa
- Spezies-Reaktivität:
- Rat
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- SDTTPCCFAYLSLALPRAHVKEYF
- Uniprot:
- P50231
- Synonyme:
- beta-chemokine RANTES;C-C motif chemokine 5;chemokine (C-C motif) ligand 5;D17S136E;eoCP;eosinophil chemotactic cytokine;RANTES;regulated upon activation normal T-cell expressed and secreted;regulated upon activation, normally T-expressed, and presumably secreted;SCYA5;SIS-delta;SISd;small inducible cytokine subfamily A (Cys-Cys), member 5;small-inducible cytokine A5;T-cell specific protein p288;T-cell-specific protein RANTES;TCP228
- Weitere Details:
- This gene is one of several chemokine genes clustered on the q arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immune regulation and inflammatory processes. According to the arrangement of N-terminal cysteine residues in mature peptides, the superfamily is divided into four subfamilies. This chemotactic factor belongs to the CC subfamily and is a chemotactic agent for blood monocytes, memory T helper cells, and eosinophils. It causes basophils to release histamine and activate eosinophils. This cytokine is one of the main HIV inhibitors produced by CD8+cells. It is one of the natural ligands of chemokine receptor chemokine receptor 5 (CCR5), which inhibits in vitro replication of HIV-1 R5 strains using CCR5 as a co receptor. Optional splicing leads to multiple transcriptional variants encoding different isomers.
- Versandbedingungen:
- Blue Ice