[KO Validated] TRIM21/SS-A Rabbit monoclonal antibody

Größe

Auf Anfrage

SKU:: A24737
Zusätzliche Namen:: -A|RNF81|Ro/SSA|RO52|SSA|SSA1
Anwendung:: ELISA, WB
Molekulargewicht:: 54 kda
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: GTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGA
Uniprot:: P19474
Synonyme:: 52 kDa ribonucleoprotein autoantigen Ro/SS-A;52 kDa Ro protein;E3 ubiquitin-protein ligase TRIM21;RING finger protein 81;RING-type E3 ubiquitin transferase TRIM21;RNF81;ro(SS-A);Ro/SSA;Ro/SSA 52kDa;RO52;Sicca syndrome antigen A;sjoegren syndrome type A antigen;Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro);SS-A;SSA;SSA1;tripartite motif-containing protein 21
Weitere Details:: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Versandbedingungen:: Blue Ice