Importin Alpha 5/KPNA1 Rabbit monoclonal antibody

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SKU:: A24117
Zusätzliche Namen:: Importin Alpha 5/KPNA1|IPOA5|NPI-1|RCH2|SRP1
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 62kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRR
Uniprot:: P52294
Synonyme:: importin alpha 5;importin subunit alpha-1;importin subunit alpha-5;importin-alpha-S1;IPOA5;karyopherin alpha 1 (importin alpha 5);Karyopherin subunit alpha-1;NPI-1;nucleoprotein interactor 1;RAG cohort protein 2;RCH2;recombination activating gene cohort 2;SRP1;SRP1-beta
Weitere Details:: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Versandbedingungen:: Blue Ice