HRP-conjugated Digoxin Rabbit monoclonal antibody

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SKU:: A24114
Zusätzliche Namen:: Digoxin|HRP-conjugated Digoxin
Anwendung:: ELISA, Dot blot
Molekulargewicht:: Refer to figures
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Immunogen:: Chemical compounds corresponding to Digoxin.
Formulierung:: Unmodified
Sequenz:: Digoxin conjugated to KLH
Weitere Details:: Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c, caspases 8 and 3.