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A24008

Collagen IV Rabbit monoclonal antibody

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SKU:
A24008
Zusätzliche Namen:
ATS2|BFH|BFH1|CA44|Collagen IV
Anwendung:
ELISA, WB, Dot blot
Molekulargewicht:
164 kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
AQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGRQGTCHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKISRCQVCVKYS
Uniprot:
P02462, P08572, P53420, Q14031
Synonyme:
arresten;ATS2;BFH;BSVD;BSVD1;BSVD2;CA44;canstatin;COL4A1 NC1 domain;COL4A1s;collagen alpha-1(IV) chain;collagen alpha-2(IV) chain;collagen alpha-4(IV) chain;collagen alpha-6(IV) chain;collagen IV, alpha-1 polypeptide;Collagen IV, alpha-4 polypeptide;collagen IV, alpha-6 polypeptide;collagen of basement membrane, alpha-1 chain;collagen of basement membrane, alpha-4 chain;collagen of basement membrane, alpha-6;collagen, type IV, alpha 4;collagen, type IV, alpha 6;CXDELq22.3;DELXq22.3;DFNX6;dJ889N15.4 (Collagen Alpha 6(IV));ICH;PADMAL;POREN2;RATOR
Weitere Details:
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.
Versandbedingungen:
Blue Ice