Pepsinogen I (PG I) Rabbit monoclonal antibody

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SKU:: A23155
Zusätzliche Namen:: Pepsinogen I (PG I)|Pepsinogen-4
Anwendung:: ELISA, IHC-P, IF
Molekulargewicht:: Refer to figures
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P0DJD7
Synonyme:: pepsin A-4;pepsinogen 4, group I (pepsinogen A);pepsinogen-4;pregnancy-associated glycoprotein
Weitere Details:: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.