Cytokeratin 8 Rabbit monoclonal antibody

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£169.00

SKU:: A23133
Zusätzliche Namen:: CARD2|CK-8|CK8|CYK8|Cytokeratin 8 (KRT8)|K2C8|K8|KO
Anwendung:: ELISA, Flow Cytometry, WB, IF, ICC
Molekulargewicht:: 55 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P05787
Synonyme:: CARD2;CK-8;CK8;CYK8;cytokeratin-8;K2C8;K8;keratin 8, type II;Keratin-8;keratin, type II cytoskeletal 8;KO;type-II keratin Kb8
Weitere Details:: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.