SMURF2 Rabbit monoclonal antibody

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SKU:: A2278
Zusätzliche Namen:: E3 ubiquitin-protein ligase SMURF2|SMURF2
Anwendung:: ELISA, WB, IHC-P, IP
Molekulargewicht:: 86kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: PLSCFVDENTPISGTNGATCGQSSDPRLAERRVRSQRHRNYMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSN
Uniprot:: Q9HAU4
Synonyme:: E3 ubiquitin ligase SMURF2;E3 ubiquitin-protein ligase SMURF2;HECT-type E3 ubiquitin transferase SMURF2;hSMURF2;SMAD ubiquitination regulatory factor 2;SMAD-specific E3 ubiquitin-protein ligase 2
Weitere Details:: Enables SMAD binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent SMAD protein catabolic process. Located in nuclear speck. Part of ubiquitin ligase complex.