TCAP Rabbit monoclonal antibody

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SKU:: A22731
Zusätzliche Namen:: CMD1N|CMH25|LGMD2G|LGMDR7|T-cap|TCAP|TELE|telethonin
Anwendung:: ELISA, WB, IF
Molekulargewicht:: 19kDa/21kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
Uniprot:: O15273
Synonyme:: 19 kDa sarcomeric protein;CMD1N;CMH25;LGMD2G;LGMDR7;limb girdle muscular dystrophy 2G (autosomal recessive);T-cap;TELE;telethonin;teneurin C-terminal associated peptide;titin cap protein
Weitere Details:: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.