DNA Ligase III/LIG3 Rabbit monoclonal antibody

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SKU:: A22136
Zusätzliche Namen:: DNA Ligase III/LIG3|LIG2|LIG3alpha|MTDPS20
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 96kDa(DNA Ligase III B Beta); 103kDa(DNA Ligase III A Alpha)
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: IASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCP
Uniprot:: P49916
Synonyme:: DNA ligase 3;DNA ligase III;LIG2;LIG3alpha;ligase II, DNA, ATP-dependent;ligase III, DNA, ATP-dependent;polydeoxyribonucleotide synthase [ATP] 3
Weitere Details:: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.