A21984
INSR/IGF1R Rabbit monoclonal antibody
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- SKU:
- A21984
- Zusätzliche Namen:
- CD220|CD221|HHF5|IGFIR|IGFR|INSR/IGF1R|JTK13
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 97kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- LVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
- Uniprot:
- P06213, P08069
- Synonyme:
- CD220;CD221;HHF5;IGF-I receptor;IGFIR;IGFR;insulin receptor;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IR;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Weitere Details:
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice