PGC1A Alpha Rabbit monoclonal antibody

Größe

Auf Anfrage

SKU:: A20995
Zusätzliche Namen:: LEM6|PGC-1(alpha)|PGC-1alpha|PGC-1v|PGC1|PGC1A|PGC1A Alpha|PPARGC1
Anwendung:: ELISA, WB
Molekulargewicht:: 100kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: QGNNSTKKGPEQSELYAQLSKSSVLTGGHEERKTKRPSLRLFGDHDYCQSINSKTEILINISQELQDSRQLENKDVSSDWQGQICSSTDSDQCYLRETLEASKQVSPCSTRKQLQDQEIRAELNKHFGHPSQAVFDDEADK
Uniprot:: Q9UBK2
Synonyme:: L-PGC-1alpha;LEM6;Ligand effect modulator 6;ligand effect modulator-6;peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext;peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a;peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT;peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PGC-1-alpha;PGC-1(alpha);PGC-1alpha;PGC-1v;PGC1;PGC1A;PPAR gamma coactivator variant form;PPARgamma coactivator 1alpha;PPARGC-1-alpha;PPARGC1
Weitere Details:: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Versandbedingungen:: Blue Ice