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A1975

PSMB5 Rabbit polyclonal antibody

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£152.00

SKU:
A1975
Zusätzliche Namen:
LMPX|MB1|PSMB5
Anwendung:
ELISA, WB, IHC-P, IF, ICC, IP
Molekulargewicht:
22kDa/28kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
Uniprot:
P28074
Synonyme:
LMPX;macropain epsilon chain;MB1;multicatalytic endopeptidase complex epsilon chain;proteasome (prosome, macropain) subunit, beta type, 5;proteasome beta 5 subunit;proteasome catalytic subunit 3;proteasome chain 6;proteasome epsilon chain;proteasome subunit beta 5;proteasome subunit beta type-5;proteasome subunit MB1;proteasome subunit X;proteasome subunit, beta type, 5;PSX large multifunctional protease X;testicular tissue protein Li 153;X
Weitere Details:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice