[KO Validated] cIAP1 Rabbit monoclonal antibody

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SKU:: A19688
Zusätzliche Namen:: API1|c-IAP1|cIAP1|Hiap-2|HIAP2|MIHB|P1|RNF48
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 70kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPI
Uniprot:: Q13490
Synonyme:: API1;apoptosis inhibitor 1;baculoviral IAP repeat-containing protein 2;c-IAP1;cellular inhibitor of apoptosis 1;cIAP1;Hiap-2;HIAP2;IAP homolog B;IAP-2;inhibitor of apoptosis protein 2;MIHB;NFR2-TRAF signalling complex protein;RING finger protein 48;RING-type E3 ubiquitin transferase BIRC2;RNF48;TNFR2-TRAF-signaling complex protein 2
Weitere Details:: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.