[KO Validated] ATG5 Rabbit monoclonal antibody

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SKU:: A19677
Zusätzliche Namen:: APG5|APG5-LIKE|APG5L|ASP|G5|hAPG5|SCAR25
Anwendung:: ELISA, WB, IHC-P, IF, IP
Molekulargewicht:: 55kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNI
Uniprot:: Q9H1Y0
Synonyme:: APG5;APG5 autophagy 5-like;APG5-LIKE;APG5L;apoptosis-specific protein;ASP;ATG5 autophagy related 5 homolog;autophagy protein 5;hAPG5;SCAR25
Weitere Details:: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.