A19002
BTK Rabbit monoclonal antibody
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Auf Anfrage
- SKU:
- A19002
- Zusätzliche Namen:
- AGMX1|AT|ATK|BPK|BTK|IGHD3|IMD1|PSCTK1|XLA
- Anwendung:
- ELISA, WB, IHC-P, IF
- Molekulargewicht:
- 76 kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- PVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
- Uniprot:
- Q06187
- Synonyme:
- agammaglobulinaemia tyrosine kinase;Agammaglobulinemia tyrosine kinase;AGMX1;AT;ATK;B-cell progenitor kinase;BPK;Bruton agammaglobulinemia tyrosine kinase;Bruton tyrosine kinase;Bruton's tyrosine kinase;dominant-negative kinase-deficient Brutons tyrosine kinase;IGHD3;IMD1;PSCTK1;truncated Bruton agammaglobulinemia tyrosine kinase;tyrosine-protein kinase BTK;XLA
- Weitere Details:
- The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice