A18590
TSN Rabbit polyclonal antibody
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£152.00
- SKU:
- A18590
- Zusätzliche Namen:
- BCLF-1|C3PO|RCHF1|REHF-1|TBRBP|TRSLN|TSN
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Molekulargewicht:
- 26kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Sequenz:
- GFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASE
- Uniprot:
- Q15631
- Synonyme:
- BCLF-1;C3PO;component 3 of promoter of RISC;RCHF1;recombination hotspot associated factor;recombination hotspot-binding protein;REHF-1;TBRBP;testis brain-RNA binding protein;translin;TRSLN
- Weitere Details:
- This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice