PDE3A Rabbit polyclonal antibody

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£152.00

SKU:: A17919
Zusätzliche Namen:: CGI-PDE|CGI-PDE A|CGI-PDE-A|HTNB|PDE3A
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 125 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Sequenz:: LLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWNNPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYA
Uniprot:: Q14432
Synonyme:: cAMP phosphodiesterase, myocardial cGMP-inhibited;CGI-PDE;CGI-PDE A;CGI-PDE-A;cGMP-inhibited 3',5'-cyclic phosphodiesterase A;cyclic GMP-inhibited phosphodiesterase A;HTNB;phosphodiesterase 3A, cGMP-inhibited
Weitere Details:: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Versandbedingungen:: Blue Ice