A1767
AIRE Rabbit polyclonal antibody
Größe
£152.00
- SKU:
- A1767
- Zusätzliche Namen:
- AIRE|AIRE1|APECED|APS1|APSI|PGA1
- Anwendung:
- ELISA, WB, IF, ICC
- Molekulargewicht:
- 55kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- HALADHDVVPEDKFQETLHLKEKEGCPQAFHALLSWLLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSFPKDVDLSQPRKGRKPPAVPKALVPPPRLPT
- Uniprot:
- O43918
- Synonyme:
- AIRE1;APECED;APS1;APSI;autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;autoimmune regulator;PGA1
- Weitere Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- Versandbedingungen:
- Blue Ice