ERVW-1 Rabbit polyclonal antibody

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£152.00

SKU:: A16522
Zusätzliche Namen:: ENV|ENVW|ERVW-1|ERVWE1|HERV-7q|HERV-W-ENV|HERV7Q|HERVW|HERVWENV
Anwendung:: ELISA, WB
Molekulargewicht:: 60kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: PVPEQWNNFSTEINTTSVLVGPLVSNLEITHTSNLTCVKFSNTTYTTNSQCIRWVTPPTQIVCLPSGIFFVCGTSAYRCLNGSSESMCFLSFLVPPMTIYTEQDLYSYVISKPRNKRVPILPFVIGAGVLGALGTGIGGITTSTQFYYKLSQELNGDMERVADSLVTLQDQLNSLAAVVLQNRRALDLLTAERGGTCLFLGEECCYYVNQSGIVTEKVKEIRDRIQRRAEELRNTGPWGLLSQWMPWILPFLGPLAAIILLLLFGPCIFNLLVNFVSSRIEAVKLQMEPKMQSKTKIYRR
Uniprot:: Q9UQF0
Synonyme:: endogenous retroviral family W, env(C7), member 1;Endogenous retrovirus group W member 1;endogenous retrovirus group W, member 1;ENV;Env-W;envelope glycoprotein;envelope polyprotein gPr73;enverin;ENVW;ERVWE1;HERV-7q;HERV-7q envelope protein;HERV-tryptophan envelope protein;HERV-W Env glycoprotein;HERV-W envelope protein;HERV-W_7q21.2 provirus ancestral Env polyprotein;HERV-W-ENV;HERV7Q;HERVW;HERVWENV;human endogenous retrovirus W envC7-1 envelope protein;Syncytin;syncytin-1
Weitere Details:: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Versandbedingungen:: Blue Ice