A1620
DPYD Rabbit polyclonal antibody
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£152.00
- SKU:
- A1620
- Zusätzliche Namen:
- DHP|DHPDHASE|DPD|DPYD|DYPD
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 112kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL
- Uniprot:
- Q12882
- Synonyme:
- DHP;DHPDHASE;dihydropyrimidine dehydrogenase [NADP(+)];dihydrothymine dehydrogenase;dihydrouracil dehydrogenase;DPD
- Weitere Details:
- The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice