A16149
PVRL4 Rabbit polyclonal antibody
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£152.00
- SKU:
- A16149
- Zusätzliche Namen:
- EDSS1|LNIR|nectin-4|PRR4|PVRL4
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 62kDa/75kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVL
- Uniprot:
- Q96NY8
- Synonyme:
- EDSS1;Ig superfamily receptor LNIR;LNIR;nectin 4;Nectin cell adhesion molecule 4;nectin-4;poliovirus receptor-related 4;poliovirus receptor-related protein 4;PRR4;PVRL4
- Weitere Details:
- This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
- Versandbedingungen:
- Blue Ice