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A16050

RAPGEF1 Rabbit polyclonal antibody

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£152.00

SKU:
A16050
Zusätzliche Namen:
C3G|GRF2|RAPGEF1
Anwendung:
ELISA, WB, IF, ICC
Molekulargewicht:
120kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
ARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
Uniprot:
Q13905
Synonyme:
C3G;CRK SH3-binding GNRP;GRF2;Guanine nucleotide-releasing factor 2;guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene);Protein C3G;Rap guanine nucleotide exchange factor (GEF) 1;rap guanine nucleotide exchange factor 1
Weitere Details:
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Versandbedingungen:
Blue Ice