DICER1 Rabbit polyclonal antibody

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£152.00

SKU:: A15799
Zusätzliche Namen:: aviD|DCR1|Dicer|DICER1|Dicer1e|GLOW|HERNA|K12H4.8-LIKE|MNG1|RMSE2
Anwendung:: ELISA, IF, ICC
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: KSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGN
Uniprot:: Q9UPY3
Synonyme:: aviD;DCR1;Dicer;dicer 1, double-stranded RNA-specific endoribonuclease;dicer 1, ribonuclease type III;Dicer1, Dcr-1 homolog;Dicer1e;endoribonuclease Dicer;GLOW;helicase MOI;helicase with RNAse motif;HERNA;K12H4.8-LIKE;MNG1;RMSE2
Weitere Details:: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants.