A1578
Factor IX / F9 Rabbit polyclonal antibody
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£152.00
- SKU:
- A1578
- Zusätzliche Namen:
- F9 p22|Factor IX / F9|FIX|HEMB|P19|PTC|THPH8
- Anwendung:
- ELISA, WB, IF
- Molekulargewicht:
- 52kDa/66kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- TVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRA
- Uniprot:
- P00740
- Synonyme:
- Christmas factor;coagulation factor IX;F9 p22;factor 9;factor IX F9;FIX;HEMB;P19;plasma thromboplastic component;plasma thromboplastin component;PTC;THPH8
- Weitere Details:
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
- Versandbedingungen:
- Blue Ice