SMPD4 Rabbit polyclonal antibody

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£152.00

SKU:: A15473
Zusätzliche Namen:: NEDMABA|NEDMEBA|NET13|NSMASE-3|NSMASE3|SKNY|SMPD4
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 100kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: ITQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHLTEPGLASRHLLSPVGRRQVA
Uniprot:: Q9NXE4
Synonyme:: NEDMABA;NEDMEBA;NET13;neutral sphingomyelinase 3;neutral sphingomyelinase III;NSMASE-3;NSMASE3;SKNY;sphingomyelin phosphodiesterase 4;sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Weitere Details:: The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.