ERLIN1 Rabbit polyclonal antibody

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£152.00

SKU:: A14843
Zusätzliche Namen:: C10orf69|Erlin-1|ERLIN1|KE04|KEO4|SPFH1|SPG62
Anwendung:: ELISA, WB, IHC-P, IP
Molekulargewicht:: 39kda
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: KADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG
Uniprot:: O75477
Synonyme:: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9;C10orf69;endoplasmic reticulum lipid raft-associated protein 1;erlin-1;KE04;KEO4;Protein KE04;SPFH domain family, member 1;SPFH domain-containing protein 1;SPFH1;SPG62;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Weitere Details:: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.