CBFA2T3 Rabbit polyclonal antibody

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£152.00

SKU:: A14712
Zusätzliche Namen:: CBFA2T3|ETO2|MTG16|MTGR2|RUNX1T3|ZMYND4
Anwendung:: ELISA, WB
Molekulargewicht:: 75kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: GQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR
Uniprot:: O75081
Synonyme:: CBFA2/RUNX1 translocation partner 3;core-binding factor, runt domain, alpha subunit 2; translocated to, 3;ETO2;MTG16;MTG8-related gene 2;MTG8-related protein 2;MTGR2;myeloid translocation gene 8 and 16b;myeloid translocation gene on chromosome 16 protein;protein CBFA2T3;RUNX1T3;zinc finger MYND domain-containing protein 4;ZMYND4
Weitere Details:: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Versandbedingungen:: Blue Ice