ZAK Rabbit polyclonal antibody

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£152.00

SKU:: A14513
Zusätzliche Namen:: AZK|CNM6|MLK7|mlklak|MLT|MLTK|MLTKalpha|MLTKbeta|MRK|pk|SFMMP|ZAK
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 105kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: EEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERE
Synonyme:: AZK;CNM6;HCCS-4;human cervical cancer suppressor gene 4 protein;mitogen-activated protein kinase kinase kinase 20;mitogen-activated protein kinase kinase kinase MLT;mixed lineage kinase 7;mixed lineage kinase with a leucine zipper and a sterile alpha motif;mixed lineage kinase-related kinase MRK-beta;MLK-like mitogen-activated protein triple kinase;MLK7;mlklak;MLT;MLTK;MLTKalpha;MLTKbeta;MRK;pk;SFMMP;sterile alpha motif and leucine zipper containing kinase AZK;ZAK;ZAK1 homolog, leucine zipper and sterile-alpha motif kinase
Weitere Details:: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Versandbedingungen:: Blue Ice