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A13930

PAX3 Rabbit polyclonal antibody

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£152.00

SKU:
A13930
Zusätzliche Namen:
CDHS|HUP2|PAX-3|PAX3|WS1|WS3
Anwendung:
ELISA, WB
Molekulargewicht:
53kda
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
QSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLDHMKSLDS
Uniprot:
P23760
Synonyme:
CDHS;HUP2;paired box homeotic gene 3;paired box protein Pax-3;paired domain gene 3;paired domain gene HuP2;transcriptional factor PAX3;WS1;WS3
Weitere Details:
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Versandbedingungen:
Blue Ice