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A12789

PDIA2 Rabbit polyclonal antibody

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£152.00

SKU:
A12789
Zusätzliche Namen:
PDA2|PDI|PDIA2|PDIP|PDIR
Anwendung:
ELISA, WB, IF, ICC
Molekulargewicht:
58kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
FGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
Uniprot:
Q13087
Synonyme:
pancreas-specific protein disulfide isomerase;pancreatic protein disulfide isomerase;PDA2;PDI;PDIP;PDIR;protein disulfide isomerase-associated 2;protein disulfide isomerase, pancreatic;protein disulfide-isomerase A2;Rho GDP dissociation inhibitor gamma
Weitere Details:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.
Versandbedingungen:
Blue Ice