A12684
Aromatase (CYP19A1) Rabbit polyclonal antibody
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£152.00
- SKU:
- A12684
- Zusätzliche Namen:
- ARO|ARO1|Aromatase (CYP19A1)|CPV1|CYAR|CYP19|CYPXIX|P-450AROM
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Molekulargewicht:
- 58 kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTN
- Uniprot:
- P11511
- Synonyme:
- ARO;ARO1;aromatase;CPV1;CYAR;CYP19;CYPXIX;cytochrome P-450AROM;cytochrome P450 19A1;cytochrome P450, family 19, subfamily A, polypeptide 1;cytochrome P450, subfamily XIX (aromatization of androgens);estrogen synthase;estrogen synthetase;flavoprotein-linked monooxygenase;microsomal monooxygenase;P-450AROM
- Weitere Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
- Versandbedingungen:
- Blue Ice