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A12596

ASAH2 Rabbit polyclonal antibody

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£152.00

SKU:
A12596
Zusätzliche Namen:
ASAH2|BCDase|HNAC1|LCDase|N-CDase|NCDase
Anwendung:
ELISA, WB
Molekulargewicht:
85kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
TATQTSPVPLTPESPLFQNFSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGP
Uniprot:
Q9NR71
Synonyme:
acylsphingosine deacylase 2;BCDase;HNAC1;LCDase;mitochondrial ceramidase;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2;N-acylsphingosine amidohydrolase 2;N-CDase;NCDase;neutral ceramidase;neutral/alkaline ceramidase;non-lysosomal ceramidase
Weitere Details:
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
Versandbedingungen:
Blue Ice