OGDH Rabbit polyclonal antibody

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£152.00

SKU:: A12477
Zusätzliche Namen:: AKGDH|E1k|E1o|KGD1|OGDC|OGDH|OGDH-E1|OGDH2|OGDHD
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 116kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: DPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVRPRERRARQIVKAPCSSMEFRSPT
Uniprot:: Q02218
Synonyme:: 2-oxoglutarate dehydrogenase complex component E1;2-oxoglutarate dehydrogenase, mitochondrial;AKGDH;Alpha-ketoglutarate dehydrogenase;E1k;KGD1;OGDC;OGDC-E1;OGDH2;oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide);oxoglutarate decarboxylase;oxoglutarate dehydrogenase (succinyl-transferring);testicular tissue protein Li 131
Weitere Details:: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Versandbedingungen:: Blue Ice