RRBP1 Rabbit polyclonal antibody

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£152.00

SKU:: A12239
Zusätzliche Namen:: ES/130|ES130|hES|p180|RRBP1|RRp
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 120kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDPAPNVTVLLREPVRAPAVAVAPTPVQPPIIVAPVATVPAMPQEKLASSPKDKK
Uniprot:: Q9P2E9
Synonyme:: 180 kDa ribosome receptor homolog;endoplasmic reticulum ribosome-binding protein 1;ES/130;ES/130-related protein;ES130;hES;p180;ribosomal receptor-binding protein 1;ribosome binding protein 1 homolog 180kDa (dog);ribosome receptor protein;ribosome-binding protein 1;RRp
Weitere Details:: This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.

Versandbedingungen:: Blue Ice