[KO Validated] DNAJA1 Rabbit polyclonal antibody

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SKU:: A11602
Zusätzliche Namen:: A1|DJ-2|DjA1|hDJ-2|HDJ2|HSDJ|HSJ-2|HSJ2|HSPF4|NEDD7
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 45kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPRGGVQCQTS
Uniprot:: P31689
Synonyme:: DJ-2;DjA1;DnaJ (Hsp40) homolog, subfamily A, member 1;dnaJ homolog subfamily A member 1;dnaJ protein homolog 2;hDJ-2;HDJ2;heat shock 40 kDa protein 4;heat shock protein J2;heat shock protein, DNAJ-like 2;HSDJ;HSJ-2;HSJ2;HSPF4;human DnaJ protein 2;NEDD7;neural precursor cell expressed, developmentally down-regulated 7
Weitere Details:: This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes.

Versandbedingungen:: Blue Ice