Ambra1 Rabbit polyclonal antibody

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£152.00

SKU:: A1083
Zusätzliche Namen:: Ambra1|DCAF3|WDR94
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 130-150kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: GAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR
Uniprot:: Q9C0C7
Synonyme:: activating molecule in beclin-1-regulated autophagy;activating molecule in BECN1-regulated autophagy protein 1;autophagy/beclin-1 regulator 1;DCAF3;DDB1 and CUL4 associated factor 3;WD repeat domain 94;WDR94
Weitere Details:: Enables GTPase binding activity and ubiquitin protein ligase binding activity. Involved in macroautophagy; positive regulation of phosphatidylinositol 3-kinase activity; and response to mitochondrial depolarisation. Located in cytosol. Colocalizes with mitochondrion. Biomarker of multiple system atrophy.