HNRNPDL Rabbit polyclonal antibody

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£152.00

SKU:: A10721
Zusätzliche Namen:: HNRNP|HNRNPDL|HNRPDL|JKTBP|JKTBP2|laAUF1|LGMD1G|LGMDD3
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 38kda
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: NIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
Uniprot:: O14979
Synonyme:: A+U-rich element RNA binding factor;AU-rich element RNA-binding factor;heterogeneous nuclear ribonucleoprotein D-like;HNRNP;hnRNP D-like;hnRNP DL;HNRPDL;JKT41-binding protein;JKTBP;JKTBP2;laAUF1;LGMD1G;LGMDD3;limb girdle muscular dystrophy 1G (autosomal dominant);protein laAUF1
Weitere Details:: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

Versandbedingungen:: Blue Ice