A1066
Calreticulin Rabbit polyclonal antibody
Größe
£152.00
- SKU:
- A1066
- Zusätzliche Namen:
- Calreticulin|cC1qR|CRT|HEL-S-99n|RO|SSA
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Molekulargewicht:
- 55 kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- EPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFL
- Uniprot:
- P27797
- Synonyme:
- calregulin;calreticulin;cC1qR;CRP55;CRT;endoplasmic reticulum resident protein 60;epididymis secretory sperm binding protein Li 99n;ERp60;grp60;HACBP;HEL-S-99n;RO;Sicca syndrome antigen A (autoantigen Ro; calreticulin);SSA
- Weitere Details:
- Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.
- Versandbedingungen:
- Blue Ice