LMAN1 Rabbit polyclonal antibody

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£152.00

SKU:: A10440
Zusätzliche Namen:: ERGIC-53|ERGIC53|F5F8D|FMFD1|gp58|LMAN1|MCFD1|MR60
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 55kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P49257
Synonyme:: endoplasmic reticulum-golgi intermediate compartment protein 53;ER-Golgi intermediate compartment 53 kDa protein;ERGIC-53;ERGIC53;F5F8D;FMFD1;gp58;intracellular mannose-specific lectin MR60;Lectin mannose-binding 1;MCFD1;MR60;protein ERGIC-53
Weitere Details:: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.