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A0883

Ku70 Rabbit polyclonal antibody

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£152.00

SKU:
A0883
Zusätzliche Namen:
CTC75|CTCBF|G22P1|KU70|ML8|TLAA
Anwendung:
ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:
70kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
PYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD
Uniprot:
P12956
Synonyme:
5'-deoxyribose-5-phosphate lyase Ku70;5'-dRP lyase Ku70;70 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase II 70 kDa subunit;ATP-dependent DNA helicase II, 70 kDa subunit;CTC box binding factor 75 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC75;CTCBF;DNA repair protein XRCC6;G22P1;Ku autoantigen p70 subunit;Ku autoantigen, 70kDa;KU70;lupus Ku autoantigen protein p70;ML8;thyroid autoantigen 70kD (Ku antigen);thyroid autoantigen 70kDa (Ku antigen);Thyroid-lupus autoantigen;thyroid-lupus autoantigen p70;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair cross-complementing protein 6
Weitere Details:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Versandbedingungen:
Blue Ice